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Artificial Cornea with Double-Side-Microtextured pHEMA Hydrogel Artificial Cornea with Double-Side Microtextured pHEMA Hydrogel Background As stated by World Health Organization (WHO), over 10 million people suffer from corneal blindness globally and 285 million people are visually impaired; however, only 1/50 of the patients obtained corneal transplants each year worldwide due to lack of donor tissue. In addition,... Published: 11/4/2025   |   Inventor(s): YIWEN XI, Chang-Hwan Choi, Xiaojun Yu Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Fabrication Of An Implantable Nerve Conduit Having A Polymer Fiber Spiral Guidance Channel Background:The spiral nerve guidance conduit is a biodegradable Polycaprolactone (PCL) spiral tube designed for bridging an injured peripheral nerve gap without tension and providing a large surface area for axon regrowth. In contract to our conduit, the traditional conduits support regeneration only along the tubular walls of the scaffolds which do... Published: 10/17/2025   |   Inventor(s): Xiaojun Yu, Wei Chang Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Fabrication of Injectable Nanofiber Reinforced Hydrogel Scaffold Invention Summary: The nanofiber-reinforced hydrogel scaffold is an innovative scaffold for the repair of focal cartilage defects in the articular region. It can be used as an augmentation of autologous chondrocyte implantation (ACI) by providing a vehicle for injection of the cell-laden scaffold into the defect. Compared with ACI, the nanofiber-reinforced... Published: 2/7/2014   |   Inventor(s): Hua Chen, Paul Lee, Xiaojun Yu Keywords(s):   Category(s): Medical