All Technologies  - Advanced Search   

Search Results - bio+technology+(rx%2c+dev%27s%2c+sys)

9 Results

Sort By: Published Date Updated Date Title ID Descending Ascending

Dual Modulus Scaffold Designs for Bone Graft Incorporation and Stability Background Bone is the second most transplanted tissue with approximately 2.2 million grafting procedures performed annually worldwide as a result of trauma, infection, or disease. Issues associated with the gold standard use of autografts and allografts, particularly when massive quantities are needed, have stimulated the development of synthetic... Published: 11/4/2025   |   Inventor(s): Rebecca Chung, Antonio Valdevit, Dilhan Kalyon Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Artificial Cornea with Double-Side-Microtextured pHEMA Hydrogel Artificial Cornea with Double-Side Microtextured pHEMA Hydrogel Background As stated by World Health Organization (WHO), over 10 million people suffer from corneal blindness globally and 285 million people are visually impaired; however, only 1/50 of the patients obtained corneal transplants each year worldwide due to lack of donor tissue. In addition,... Published: 11/4/2025   |   Inventor(s): YIWEN XI, Chang-Hwan Choi, Xiaojun Yu Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Conductive scaffolds for guided neural network formation Background: The present invention relates to the fabrication of patterned conductive scaffolds of micro and/or nanofibers with the help of printing techniques (e.g., near-field electrostatic printing, inkjet printing) and the formation of two-dimensional (2D) or three-dimensional (3D) neural networks guided by the conductive patterns under electrical... Published: 10/16/2025   |   Inventor(s): Hongjun Wang, Haoyu Wang, Juan Wang Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Microfluidic 3D Osteocyte Network Reconstructured With Microbeads As Scaffold Background: Mature osteocytes embedded in the three-dimensional lacuna-canalicular network (3D-LCN) structure are known to sense local compressive strain and initiate strain-dependent new bone formation by osteoblasts, utilizing cytokines such as sclerostin and Dkk1 expressed by the osteocytes as major signaling molecules. Studying these osteocytes... Published: 10/16/2025   |   Inventor(s): Woo Young Lee, Yexin Gu, Wenting Zhang, Qiaoling Sun, Jenny Zilberberg Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

An Ex Vivo Human Multiple Myeloma Cancer Niche and Its Use As a Model for Personalized Treatment of Multiple Myeloma Background:Primary patient-derived multiple myeloma cells (MMC) are difficult to preserve . Long-term survival of osteoblasts, OSB, is the most critical factor in maintaining the ex vivo viability and proliferative capacity of MMC. The adhesion and retention of MMC to the tissue scaffold was meditated by osteoblastic N-cadherin, as one of potential... Published: 10/20/2025   |   Inventor(s): Woo Young Lee, Wenting Zhang, Peter Tolias, Hongjun Wang, Jenny Zilberberg, David Siegel Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Human Immunodeficiency Virus Protease Inhibitors The described invention relates to novel human immunodeficiency virus protease inhibitors, pharmaceutical compositions containing at least one such inhibitor, methods of preparing such inhibitors, and methods of utilizing such inhibitors to treat HIV and HIV-related disorders.Full Patent: Human Immunodeficiency Virus Protease Inhibitors Published: 10/16/2025   |   Inventor(s): A.k. Ganguly, Dipshikha Biswas, Sesha Sridevi Alluri, Danielle Caroccia, Chih-Hung Wang, Eun Hee Kang Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Desorption Ionization By Charge Exchange (Dice) For Sample Analysis Under Ambient Conditions By Mass Spectrometry Background:Recent developments in ambient desorption ionization techniques, such as desorption electrospray ionization, DESI, and direct analysis in real time, DART, have opened new routes for characterizing a wide range of compounds, such as proteins, explosives, polymers, pharmaceuticals and metabolites amenable to mass spectrometry, with little or... Published: 2/2/2026   |   Inventor(s): Chang-Ching Chan, Athula Attygalle, Mark Bolgar, Soctt Miller Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Fabrication Of An Implantable Nerve Conduit Having A Polymer Fiber Spiral Guidance Channel Background:The spiral nerve guidance conduit is a biodegradable Polycaprolactone (PCL) spiral tube designed for bridging an injured peripheral nerve gap without tension and providing a large surface area for axon regrowth. In contract to our conduit, the traditional conduits support regeneration only along the tubular walls of the scaffolds which do... Published: 10/17/2025   |   Inventor(s): Xiaojun Yu, Wei Chang Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)

Methods For Lung-Protective Mechanical Ventilation Background:The terminal airspaces of the lungs, the alveoli, are lined with a thin liquid layer. Thus there is an air-liquid interface in the lungs that has an associated surface tension. To reduce the surface tension, alveolar type II epithelial cells release surfactant—an aggregate of phospholipids and proteins—into the liquid lining layer.... Published: 10/17/2025   |   Inventor(s): Carrie Perlman Keywords(s):   Category(s): Bio Technology (Rx, dev's, sys)